科學(xué)研究：

研究方向：

1. 新型大環(huán)化合物的設(shè)計(jì)、合成、主客體性質(zhì)研究以及超分子自組裝研究；

2. 基于主客體化學(xué)構(gòu)筑有機(jī)-無(wú)機(jī)雜化的納米材料在生物醫(yī)學(xué)上的應(yīng)用；

3. 納米尺度多孔框架材料（MOFs、COFs、SOFs等）的可控合成及 其在生物醫(yī)學(xué)上的應(yīng)用研究；

4. 基于多孔晶態(tài)相變材料的合成及其在能量存儲(chǔ)與轉(zhuǎn)換方面的應(yīng)用。

承擔(dān)科研項(xiàng)目情況：

1、主持國(guó)家自然科學(xué)基金一項(xiàng)。

2、主持江蘇省自然科學(xué)基金一項(xiàng)。                                 

科研成果：

迄今以第一作者和通訊作者論文37篇，其中包括JCR化學(xué)類一區(qū)20篇（2篇JACS，3篇Chemical Science，13 篇Chem. Commun，1篇Org. Lett.，1篇JMCB），總引用超過(guò)2367次，單篇被引用最高303次。

發(fā)明專利：

1 含吡唑結(jié)構(gòu)的氰基丙烯酸酯類化合物及其制備方法和用途  戴紅;石玉軍;杜顯超;姚勇;姚煒;陳佳;王祥龍;馮浩;樊麗余;陳慶文 南通大學(xué) 中國(guó)專利 2017-08-23 2019-11-05    

2 含噁唑聯(lián)芐氧基結(jié)構(gòu)的氰基丙烯酸酯化合物的制備和應(yīng)用  戴紅;石玉軍;姚勇;姚煒;杜顯超;方源;陳慶文;王雨陽(yáng);季允亮;陳凌杰 南通大學(xué) 中國(guó)專利 2017-08-18 2019-07-26   

3 一種基于柱芳烴主客體作用的具有近紅外光刺激響應(yīng)性的雜化超分子材料的制備方法  姚勇;石玉軍;戴紅;孫思宇 南通大學(xué) 中國(guó)專利 2018-01-09 2018-06-22    

4 含四氮唑基團(tuán)的氰基丙烯酸酯衍生物的制備和應(yīng)用  戴紅;石玉軍;杜顯超;姚煒;姚勇;陳佳;黃美嶺;孫思宇;江建華;周錢 南通大學(xué) 中國(guó)專利 2017-08-24 2018-01-19   

5 含噁唑聯(lián)芐氧基結(jié)構(gòu)的氰基丙烯酸酯化合物的制備和應(yīng)用  戴紅;石玉軍;姚勇;姚煒;杜顯超;方源;陳慶文;王雨陽(yáng);季允亮;陳凌杰 南通大學(xué) 中國(guó)專利 2017-08-18 2017-12-29   

6 含吡唑結(jié)構(gòu)的氰基丙烯酸酯類化合物及其制備方法和用途  戴紅;石玉軍;杜顯超;姚勇;姚煒;陳佳;王祥龍;馮浩;樊麗余;陳慶文 南通大學(xué) 中國(guó)專利 2017-08-23 2017-12-15   

備注：按照  專利名稱 發(fā)明人 申請(qǐng)人 來(lái)源數(shù)據(jù)庫(kù) 申請(qǐng)日 公開(kāi)日   排序

  

論文專著：

出版專著： 

資料更新中……

發(fā)表期刊論文：

2019年：

1. Cai, Y.; Wang, Y.; Wang, C.; Long, R.; Cao, L.; Chen, Y.; Yao, Y.* "Hierarchical self-assembly of 3D amphiphilic discrete organoplatinum(Ⅱ) metallacage in water", Chinese Chemical Letter., DIO: 10.1016/j.cclet.2019.08.036

2. 張潤(rùn)淼, 王陳威, 孫晶, 顏朝國(guó), 姚勇. 基于柱[5]芳烴的新型雙-[1]輪烷的設(shè)計(jì)與合成[J].   有機(jī)化學(xué)  2019-08-08  

3. Yang Wang,† Yan Cai,† Leyu Cao,† Moupan Cen, Yanmei Chen, Runmiao Zhang, Tingting Chen,* Hong Dai,* Lanping Hu* and Yong Yao*, An amphiphilic metallaclip with enhanced fluorescence emission in water: synthesis and controllable self-assembly into multi-dimensional micro-structures, Chem. Comm., 2019, 55, 10132-10134.

4. Zhang, R.; Wang, C.; Long, R.; Chen, T.*; Yan, C.*; Yao, Y.* "Pillar[5]arene based [1]rotaxane systems with redox-responsive host-guest property: design, synthesis and the key role of chain length",DOI: 10.3389/fchem.2019.00508.

5. Chen, J.; Wang, Y.; Wang, C.; Long, R.; Chen, T.*; Yao, Y.* "Functionalization of inorganic nanomaterials with pillar[n]arenes". Chem. Comm., 2019, 55, 6817-6826.

6. Wang, Y.; Liu, T.; Jiang, J.; Chen, Y.; Cen, M.; Lu, D.; Cao, L.; Sun, S.; Yao, Y.* “Syntheses of water soluble acyclic naphthalene oligomers and their application in water”, Dalton Trans., 2019, 48, 6333-6336.

7. Sun, S.; Lu, D.; Huang, Q.; Liu, Q.; Yao, Y.*; Shi, Y.* “Reversible surface activity and self-assembly behavior and transformation of amphiphilic ionic liquids in water induced by a pillar[5]arene-based host-guest interaction”, J. Colloid. Interf. Sci., 2019, 533, 42-46.

8. Wang, Y.; Wang, C.; Long, R.; Cao, Y.; Fan, D.; Cen, M.; Cao, L.; Chen, Y.; Yao, Y.* “Synthesis and controllable self-assembly of 3D amphiphilic organoplatinum (II) metallacages in water”, Chem. Comm., 2019, 55, 5167-5170.

9. Dai, H.; Huang, M.; Qian, J.; Liu, J.; Meng, C.; Li, Y.; Ming, G.; Zhang, T.; Wang, S.; Shi, Y.; Yao, Y.*; Ge, S.; Zhang, Y.; Ling, Y.* “Excellent antitumor and antimetastatic activities based on novel coumarin/pyrazole hybrids” European Journal of Medicinal Chemistry, 2019, 166, 470-479.

10. Chen, Y.; Sun, S.; Lu, D.; Shi, Y.; Yao, Y.;* “Water-soluble supramolecular polymers constructed by macrocycle-based host-guest interactions” Chin. Chem. Lett., 2019, 30, 37-43.

2018年：

11. Yao, Y.*; Wei, X.; Chen, J.; Dai, H.; Shi, Y. “Amphiphilic pillar[n]arenes” Supramolecular Chemistry 2018, 7, 610-618.

12. Yao, Y.*; Wei, X.; Cai, Y.; Kong, X.; Chen, J.; Wu, J.; Shi, Y. “Hybrid supramolecular materials constructed from pillar[5]arene based host-guest interactions with photo and redox tunable properties” J. Colloid. Interf. Sci., 2018, 525, 48-53.

13. Yao, Y.*; Zhao, R.; Shi, Y.; Cai, Y.; Chen, J.; Sun, S.; Zhang, W.*; Tang, R.* “2D amphiphilic organoplatinum(II) metallacycles: syntheses, self-assembly in water and their potential application in photodynamic therapy”, Chem. Commun., 2018, 54, 8068-8071.

14. Zhou, J.; Dai, H.*; Qian, H.; Du, X.; Mao, X.; Shi, Y.*; Feng, H.; Shi, J.; Yao, Y.* “Synthesis and Biological Activity of New Cyanoacrylate Compounds Bearing Oxazole Moiety”, Chin. J. Org. Chem., 2018, 38, 2122-2129.

15. Sun, Y.*#; Yao, Y.#; Wang, H.; Fu, W.; Chen, C.; Sasa, M. L.; Zhang, M.; Datta, S.; Zhou, Z.; Yu, H.; Li, X.; Stang, P. J.* “Self-Assembly of Metallacages into Multidimensional Suprastructures with Tunable Emissions”, J. Am. Chem. Soc., 2018, 140, 12819−12828. (共一).

16. Sun, S.; Geng, M.; Huang, L.; Chen, Y.; Cen, M.; Lu, D.; Wang, A.; Wang, Y.;* Shi, Y.; Yao, Y.* “A new amphiphilic pillar[5]arene: synthesis, controllable selfassembly in water and application in white-light-emitting system ” Chem. Commun., 2018, 54, 13006-13009.

17.周家華; 戴紅; 錢宏煒; 杜顯超; 茅心宇; 石玉軍; 馮浩; 石健; 姚勇 新型含噁唑環(huán)結(jié)構(gòu)的氰基丙烯酸酯類衍生物的合成及其生物活性研究     有機(jī)化學(xué)  2018-07-02

2017年：

18. Xu. H.; Yao, Y.* “Supramolecular amphiphilies based on water-soluble pillar[5]arene/paraquat derivatives and their self-assembly behaviour in water” Supramolecular Chemistry 2017, 3, 161-166.

19. Sun. Y.*; Wang, J.; Yao, Y.* “First water-soluble pillar[5]arene dimer: synthesis and construction of a reversible fluorescent supramolecular polymer network in water” Chem. Commun., 2017, 53，165-167.

20. Zhou. Y.; Jie, K.; Yao, Y.* “A cavity extended water-soluble resorcin[4]arene: synthesis, pH-controlled complexation with paraquat, and application in controllable self-assembly” New J. Chem., 2017, 41, 916-919.

21. Sun, Y.*; Fu, W.; Chen, C.; Wang, J.; Yao, Y.* “Water-soluble pillar[5]arene induced the morphology transformation of self-assembled nanostructures and further application in paraquat detection” Chem. Commun., 2017, 53,3725-3728.

22. Yao, Y.*; Sun, Y.; Yu, H.; Chen, W.; Dai, H.; Shi, Y.* “A pillar[5]arene based gel from a low-molecular-weight gelator for sustained dye release in water” Dalton Trans., 2017, 46, 16802-16806.

23. Yu, G.; Zhang, M.; Saha, M. L.; Mao, Z.; Chen, J.; Yao, Y.; Zhou, Z.; Liu, Y.; Gao, C.; Huang, F.*; Chen, X.*; Stang, P. J.* “Antitumor Activity of a Unique Polymer That Incorporates a Fluorescent Self-Assembled Metallacycle” J. Am. Chem. Soc., 2017, 139, 15940–15949.

2016年：

24. Yao, Y.; Wang, Y.; Zhao, R.; Shao, L.; Tang, R.*; Huang, F.* “Improved in vivo tumor therapy via host-guest complexation” J. Mater. Chem. B, 2016, 4, 2691-2696.

25. Xia, D.; Li, Y.; Jie, K.; Shi, B.; Yao, Y.* “A Water-Soluble Cyclotriveratrylene-Based Supra-amphiphile: Synthesis, pH-Responsive Self-Assembly in Water, and Its Application in Controlled Drug Release” Org. Lett., 2016, 18, 2910-2913.

2015年：

26. Zhou, Y.; Jie, K.; Shi, B.; Yao, Y.* “A γ-ray and dual redox-responsive supramolecular polymer constructed by a selenium containing pillar[5]arene dimer and a neutral guest” Chem. Commun., 2015, 51, 11112-11114.

27. Jie, K.; Zhou, Y.; Shi, B.; Yao, Y.* “A Cu2+ specific metallohydrogel: preparation, multi-responsiveness and pillar[5]arene-induced morphology transformation” Chem. Commun., 2015, 51, 8461-8464.

28. Shi, B.; Jie, K.; Zhou, Y.; Xia, D.; Yao, Y.* “Formation of fluorescent supramolecular polymeric assemblies via orthogonal pillar[5]arene-based molecular recognition and metal ion coordination” Chem. Commun., 2015, 51, 4503-4506.

29. Zhou, Y.; Jie, K.; Thompson, C.; Yao, Y.* “An Ag2O-responsive [2]pseudorotaxane based on the pillar[5]arene/bis(imidazolium) dication molecular recognition motif” Tetrahedron Letters, 2015, 16, 2091–2093.

30. Jie, K.; Zhou, Y.; Yao, Y.; Huang, F.* “Macrocyclic amphiphiles” Chem. Soc. Rev., 2015, 44, 3568-3587.

31. Jie, K.; Zhou, Y.; Yao, Y.; Shi, B.; Huang, F.* “CO2-Responsive Pillar[5]arene-Based Molecular Recognition in Water: Establishment and Application in Gas-Controlled Self-Assembly and Release” J. Am. Chem. Soc., 2015, 137, 10472–10475.

32. Li, L.; Yao, Y.; Sun, J.; Yan, C.-G.* “Preparation and application of tubular assemblies based on amphiphilic tetramethoxyresorcinarenes” RSC Adv., 2015, 5,102454-102461.

33. Zhou, Y.; Yao, Y.; Huang, F.* “Four pillar[5]arene constitutional isomers: Synthesis, crystal structures, and host-guest complexation of their derivatives with paraquat in water” Chin. J. Chem., 2015, 33, 356-360.

2014年：

34. Yao, Y.; Wang, Y.; Huang, F.* “Synthesis of various supramolecular hybrid nanostructures based on pillar[6]arene modified gold nanoparticles/nanorods and their application in pH- and NIR-triggered controlled release” Chem. Sci. 2014, 5, 4312-4316.

35. Yao, Y.; Chi, X.; Zhou, Y.; Huang, F.* “A bola-type supra-amphiphile constructed from a water-soluble pillar[5]arene and a rod–coil molecule for dual fluorescent sensing” Chem. Sci. 2014, 4, 2778–2782.

36. Yao, Y.; Zhou, Y.; Dai, J.; Yue, S.; Xue, M.* “Host–guest recognition-induced color change of water-soluble pillar[5]arene modified silver nanoparticles for visual detection of spermine analogues” Chem. Commun. 2014, 50, 869–871.

37. Yao, Y.; Jie, K.; Zhou, Y.; Xue, M.* “Reversible assembly of silver nanoparticles driven by host–guest interactions based on water-soluble pillar[n]arenes” Chem. Commun. 2014, 50, 5072–5074.

38. Yao, Y.; Wei, P.; Yue, S.; Li, J.; Xue, M.* “Amphiphilic pillar[5]arenes: influence of chemical structure on self-assembly morphology and application in gas response and λ-DNA condensation” RSC Adv. 2014, 4, 6042-6047.

39. Yao, Y.; Li, J.; Dai, J.; Chi, X.; Xue, M.* “A water-soluble pillar[6]arene: synthesis, host–guest chemistry, controllable self-assembly, and application in controlled release” RSC Adv. 2014, 4, 9039-9043.

40. Yao, Y.; Jie, K.; Zhou, Y.; Xue, M.* “Water-soluble pillar[6]arene stabilized silver nanoparticles: preparation and application in amino acid detection” Tetrahedron Lett. 2014, 55, 3195-3199.

41. Zhou, Y.; Yao, Y.*; Xue, M. “Well-defined nano-sunflowers formed by self-assembly of a rod-coil amphiphile in water and their morphology transformation based on a water-soluble pillar[5]arene” Chem. Commun. 2014, 50, 8040-8042.

42. Zhou, Y.; Li, Z.; Chi, X.; Thompson, C.; Yao, Y.* “Formation of a [2]pseudorotaxane based on a pillar[5]arene and a rigid guest in solution and in the solid state” Chem. Commun. 2014, 50, 10482-10484.

43. Shi, B.; Xia, D.; Yao, Y.* “A water-soluble supramolecular polymer constructed by pillar[5]arene-based molecular recognition” Chem. Commun. 2014, 50, 13932-13935.

44. Yue, S.; Zhou, Y.; Yao, Y.;* Xue, M,* “Pillar[n]arenes: From Synthesis, Host-Guest Chemistry to Self-Assembly Properties and Applications” Acta Chim. Sinica. 2014, 72, 1053-1069.

45. Gao, L.; Yao, Y.; dong, S.; Yuan, J.* “Host–guest complexation between 1,4-dipropoxypillar[5]arene and imidazolium-based ionic liquids” RSC Adv., 2014, 4, 35489-35492.

46. Jie, K.; Yao, Y.; Chi, X.; Huang, F.* “A CO2-responsive pillar[5]arene: synthesis and self-assembly in water” Chem. Commun., 2014, 50, 5503-5505.

47. Yu, G.*; Yang, J.; Xia, D.; Yao, Y. “An enzyme-responsive supra-amphiphile constructed by pillar[5]arene/acetylcholine molecular recognition” RSC Adv., 2014, 4, 18763-18771.

48. Wang, P.; Yao, Y.; Xue, M. “A novel fluorescent probe for detecting paraquat and cyanide in water based on pillar[5]arene/10-methylacridinium iodide molecular”Chem. Commun., 2014, 50, 5064-5067.

49. Sun, J.; Zhang, L.-L.; Yao, Y.; Yan, C.-G.* “Synthesis, crystal structures and complexing properties of tetramethoxyresorcinarene functionalized tetraacylhydrazones” J. Incl. Phenom. Macro., 2014, 79, 485-494.

2013年：

50. Yao, Y.; Xue, M.; Zhang, Z.; Zhang, M.; Wang, Y.; Huang, F.* “Gold nanoparticles stabilized by an amphiphilic pillar[5]arene: preparation, self-assembly into composite microtubes in water and application in green catalysis” Chem. Sci. 2013, 4, 3667–3672.

51. Ji, X.; Yao, Y.; Li, J.; Yan, X.; Huang, F.* “A Supramolecular Cross-Linked Conjugated Polymer Network for Multiple Fluorescent Sensing” J. Am. Chem. Soc.,2013, 135, 74–77.

52. Yu, G.; Ma, Y.; Han, C.; Yao, Y.; Tang, G.; Ma, Z.; Gao, C.; Huang, F.* “A Sugar-Functionalized Amphiphilic Pillar[5]arene: Synthesis, Self-Assembly in Water, and Application in Bacterial Cell Agglutination” J. Am. Chem. Soc., 2013, 135, 10310–10313.

53. Yan, X.; Li, S.; Cook, T. R.; Ji, X.; Yao, Y.; Pollock, J. B.; Shi, Y.; Yu, G.; Li, J.; Huang, F.*; Stang, P. J.* “Hierarchical Self-Assembly: Well-Defined Supramolecular Nanostructures and Metallohydrogels via Amphiphilic Discrete Organoplatinum(II) Metallacycles” J. Am. Chem. Soc., 2013, 135 , 14036–14039.

54. Dong, S.; Zheng, B.; Yao, Y.; Han, C.; Yuan, J.* “LCST-Type Phase Behavior Induced by Pillar[5]arene/Ionic Liquid Host–Guest Complexation” Adv. Mater. 2013,25, 6864–6867.

55. Gao, L.; Zheng, B.; Yao, Y.; Huang, F.* “Responsive reverse giant vesicles and gel from self-organization of a bolaamphiphilic pillar[5]arene” Soft Matter, 2013, 9, 7314-7319.

56. Chi, X.; Xue, M.; Yao, Y.; Huang, F.* “Redox-Responsive Complexation between a Pillar[5]arene with Mono(ethylene oxide) Substituents and Paraquat” Org. Lett.,2013, 15, 4722–4725.

2012年：

57. Yao, Y.; Xue, M.; Chen, J.; Zhang, M.; Huang, F.* “An Amphiphilic Pillar[5]arene: Synthesis, Controllable Self-Assembly in Water, and Application in Calcein Release and TNT Adsorption” J. Am. Chem. Soc. 2012, 134, 15712−15715.

58. Yao, Y.; Xue, M.; Chi, X.; Ma, Y.; He, J.; Abliz, Z.; Huang, F.* “A new water-soluble pillar[5]arene: synthesis and application in the preparation of gold nanoparticles” Chem. Commun. 2012, 48, 6505–6507.

59. Ma, Y.; Chi, X.; Yan, X.; Liu, J.; Yao, Y.; Chen, W.; Huang, F.*; Hou, J.-L.* “per-Hydroxylated Pillar[6]arene: Synthesis, X-ray Crystal Structure, and Host–Guest Complexation” Org. Lett., 2012, 14 , 1532–1535.

2010年：

60. Yao, Y.; Sun, Y.; Han, Y.; Yan, C.-G.* “Preparation of resorcinarene-functionalized gold nanoparticles and their catalytic activities for reduction of aromatic nitro compounds” Chin. J. Chem., 2010, 28, 705-712.

61. Sun, Y.; Yao, Y.; Yan, C.-G.*; Han, Y.; Shen, M.* “Selective Decoration of Metal Nanoparticles inside or outside of Organic Microstructures via Self-Assembly of Resorcinarene” ACS Nano, 2010, 4, 2129–2141.

2010年以前的：

62. Sun, Y.; Yan, C.-G.*; Yao, Y.; Han, Y.; Shen, M. * “Self-assembly and metallization of resorcinarene microtubes in water” Adv. Funct. Mater., 2008, 18, 3981-3990.

63. Yan, C.-G.*; Chen, W.; Chen, J.; Jiang, T.; Yao, Y. “Microwave irradiation assisted synthesis, alkylation reaction, and configuration analysis of aryl pyrogallol[4]arenes” Tetrahedron, 2007, 63, 9614-9620.

 

榮譽(yù)獎(jiǎng)勵(lì)：

1、南通大學(xué)校高層次人才。  

媒體報(bào)道：

創(chuàng)新領(lǐng)航,在超分子世界里“燭幽探微”

——記南通大學(xué)化學(xué)化工學(xué)院校聘教授姚勇

在過(guò)去50余年里,人工合成大環(huán)主體分子的研究奠定了超分子化學(xué)的基礎(chǔ),并推動(dòng)了該學(xué)科的快速發(fā)展。大環(huán)分子的空腔大小、形狀及其電子性質(zhì)直接影響其分子識(shí)別能力和超分子組裝行為,設(shè)計(jì)與合成全新的具有多種分子識(shí)別與組裝功能的大環(huán)主體分子一直是超分子化學(xué)研究的重要挑戰(zhàn)。多年來(lái)姚勇教授和團(tuán)隊(duì)一直致力于大環(huán)主體化合物柱芳烴的合成與組裝研究,并成功合成了首個(gè)兩親型柱芳烴,其有關(guān)成果在光動(dòng)力治療中也展現(xiàn)出了良好的效果。

資料更新中…… 

來(lái)源：海峽科技與產(chǎn)業(yè) 2018年z1期